Beilstein J. Org. Chem.2016,12, 1765–1771, doi:10.3762/bjoc.12.165
the formation of the pyranose ring skeleton to give 2,7-dioxabicyclo[3.2.1]octane 12. Functional group manipulation in 12 gave 21 that on stereoselective β-glycosylation afforded the pyranosyl thymine nucleoside 2 – a core of amipurimycin.
Keywords: amipurimycin; 1,3-anhydrosugar; anti-fungalagent